QuarkXPress 7 has an amazing ability to render your layout in whatever color space you like.
The Grayscale option (View> Proof Output> Grayscale) is particularly handy for previewing how your entire layout will print in grayscale.
The other built-in profiles include RGB, CMYK, CMYK and Spot, and more.
You can create your own, or import profiles provided by your output provider, by choosing Edit> Color Setups… Output…
Jay Nelson is the editorial director of PlanetQuark.com, and the editor and publisher of Design Tools Monthly. He’s also the author of the QuarkXPress 8 and QuarkXPress 7 training titles at Lynda.com, as well as the training videos Quark includes in the box with QuarkXPress 7 . In addition, Jay writes regularly for Macworld and Photoshop User magazines and speaks at industry events.