There, you can Lock, Unlock, and Remove Guides.
You can choose to delete all vertical or horizontal guides, locked guides, or all guides. You can also choose to delete the guides from the current page, the current spread, or from all pages.
Jay Nelson is the editorial director of PlanetQuark.com, and the editor and publisher of Design Tools Monthly. He’s also the author of the QuarkXPress 8 and QuarkXPress 7 training titles at Lynda.com, as well as the training videos Quark includes in the box with QuarkXPress 7 . In addition, Jay writes regularly for Macworld and Photoshop User magazines and speaks at industry events.